Subsequent-gen fat burners and hormones assist the wealthy shed weight

When Fabiana Saba was a younger mannequin, the 5-foot, 10-inch, 100-pound stunner graced the covers of Elle and Marie Claire in her native Brazil, shared {a magazine} unfold with Gisele Bündchen and walked the runways at trend week in New York, Paris, Milan, Tokyo and St. Paolo with the likes of Alessandra Ambrosio — all earlier than turning into a TV host. As she grew into maturity, her weight rose to a still-slender 130 kilos.

However, after having two youngsters and enduring the primary few months of the pandemic, Saba discovered herself in a physique that not felt like her personal. By the second half of 2020, she weighed 186 kilos and struggled with joint ache and respiration points. 

“Like so many individuals, I began baking throughout the pandemic, and I wasn’t simply consuming one piece; I might eat the entire cake,” Saba, now 44 and dwelling on New York’s Sutton Place, advised The Put up. The prospect of dropping the burden on her personal was daunting —  “I had tried many instances previously … and it by no means went properly,” she mentioned — so she turned to her uptown neighbor, Dr. Caroline Messer.

Fabiana Saba in a green caftan
At her heaviest, Fabiana Saba skilled respiration issues and joint ache.
Glam selfie of Fabiana Saba
After mannequin Fabiana Saba’s weight ballooned to 186 kilos throughout the pandemic, she sought out therapy from endocrinologist to the celebs Caroline Messer, who helped her lose virtually 50 kilos.
Handout from Fabiana Sutton
A college of magazine covers featuring Fabiana Saba
In her heyday, Fabiana Saba was a prime mannequin, masking main trend magazines in her native Brazil.

Messer recognized her with pre-diabetes and excessive ldl cholesterol and prescribed her each an anti-anxiety remedy and an urge for food suppressant. The meds helped her drop all the way down to 137 kilos in lower than a 12 months with relative ease. 

“Having a health care provider modified the whole lot,” gushed Saba, who stays on the drugs.

Full-length photo of Fabiana Saba in a black minidress
Fabiana Saba now weight 137 kilos, because of drugs prescribed by Dr. Messer.
Handout from Fabiana Sutton

The town’s wealthy and fabulous seeking to shed weight aren’t slogging it with fad diets and Noom subscriptions. They’re spending hundreds of {dollars} to work with Messer, a famous endocrinologist whose sufferers embody Saudi royals, A-list stars, titans of business, skilled athletes and socialites seeking to slim down and supercharge their well being.

“There may be undoubtedly a pattern towards seeing endocrinologists … as a result of we have now extra remedies now that deal with hormonal imbalances that result in weight achieve,” mentioned Messer. “Lots of people suspect they’ve simply measured hormonal imbalance, however it’s usually one thing extra delicate.”

The 44-year-old has had a standard endocrinology follow on Fifth Avenue for years and she or he’s simply opened a boutique clinic, Nicely By Messer, on East sixtieth Road that takes a holistic method to managing metabolic points. Along with Messer and two different endocrinologists, it’s staffed by a psychologist, two health trainers and a dietician. A bariatric surgeon and pulmonologist are additionally accessible to sufferers.

Messer, who doesn’t take insurance coverage however is usually lined as an out-of-network expense, provides an preliminary $900 diagnostic go to, which entails a full historical past and bodily together with a thyroid panel. She then crafts a plan along with her crew finest fitted to the affected person. 

“I assess their degree of exercise and nutrient content material, in addition to whether or not they have a necessity for cognitive behavioral change,’’ mentioned Messer, who prices $450 for follow-up appointments. Visits to different members of her crew vary from $80 to $600.

Typically the Nicely by Messer plan consists of remedy. 

Headshot of Dr. Caroline Messer
An preliminary session with Dr. Caroline Messer prices $900.
Picture courtesy Nicely by Messer

Amongst her in style remedies are GLP1 and GIP, replications of hormones secreted by the intestine that set off a sense of satiety and sluggish digestion. The stylish new remedies — “Half the well-heeled ladies I see on the Higher East Facet are on these hormones for weight reduction, and they’re working” mentioned a Manhattan plastic surgeon — are notoriously expensive. However, Messer orders them from a Canadian pharmacy, lowering the value from roughly $1,400 to $250 monthly.  

Different meds in Messer’s arsenal embody Contrave, an anti-depressant accredited for weight reduction, and methamphetamines, which have been used to shed kilos for years with combined success.

“They’ve dangers however are life saving for actual binge-eating issues,” Messer mentioned. 

Marc Schwartz, the 57-year-old head of worldwide advertising and marketing for a pharmaceutical firm, turned to Messer to assist keep away from packing on the pandemic kilos. 

“I had a household historical past of diabetes, and I knew that individuals had been sitting round and gaining weight, so I needed to take the negativity occurring round me and switch it optimistic,’’ the New Rochelle resident mentioned. Messer put him on remedy to decrease his blood sugar, and she or he inspired him to grow to be an endurance runner.

“She actually motivated me, so I had an unimaginable sense of pleasure and objective,’’ mentioned Schwartz, who misplaced 23 kilos with Messer’s assist. “I went from being in peril of diabetes to regular vary. With out her assist I by no means may have completed it.’’

Doctors gathered around a desk at Well by Messer
At Nicely by Messer, sufferers have the choice of assembly with quite a few consultants, together with Dr. Barrie Weinstein (from left); registered dietitian Jean Hanks; and psychologist Dr. Jess Kovler.
Picture courtesy Nicely by Messer

Along with weight reduction well being, Nicely by Messer provides luxe well being extras, comparable to metabolic price testing, and sweetness remedies like Kybella injections to take away fats from underneath the chin. 

However, it’s the cutting-edge method to trimming down that sufferers most frequently rave about. 

”I’m not strolling any runways quickly, however I’m again to operating with my youngsters within the park,” mentioned Saba.   

Chopping-edge medicine endocrinologists prescribe for weight reduction

List of the drugs Dr. Caroline Messer prescribes to help clients slim down.
Dr. Caroline Messer prescribes a spread of capsules to assist shoppers slim down, relying on their well being.
Getty Photos


This cutting-edge weight reduction drug accommodates semaglutide, a hormone produced by the physique to set off emotions of fullness after consuming. Whereas it’s efficient — it has been proven to cut back total weight by 15% — it’s additionally costly, costing as much as $1,300 a month.


A mix tablet used to focus on meals dependancy, Contrave accommodates naltrexone — which has historically been prescribed for alcohol and drug dependence — and bupropion, an antidepressant usually offered underneath the title Wellbutrin. It was FDA accredited in 2014, however like all drugs, it comes with potential unwanted side effects, together with an elevated threat of seizures.


This controversial weight reduction drug has additionally been offered underneath the title Alli. It really works by blocking the physique from absorbing some fat, however the life-style prices are steep: It could actually trigger a spread of nasty unwanted side effects, from flatulence to fecal incontinence.


Consider it as a gastric bypass — in tablet type. Twenty minutes earlier than consuming, dieters swallow three Plenity capsules together with 16 ounces of water. As soon as within the abdomen, the capsules launch gel particles, which then broaden and forestall customers from consuming an excessive amount of by actually taking over area within the stomach. It was cleared by the FDA in 2019 and prices $98 a month.


Keep in mind Fen-Phen? Whereas the previous drug, fenfluramine, was taken off the market in 1997 for probably inflicting coronary heart injury, the urge for food suppressant phentermine continues to be accessible. However that doesn’t imply it’s risk-free. This amphetamine-like tablet can induce mania-like signs comparable to insomnia and coronary heart palpitations.


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